GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THYM | cis | rs1577917 | 1 | rs12190598 | chr6:86686074 | SNHG5 | chr6:86386726-86388451:- | -0.57 | -6.83 | 7.85E-10 | Response to antipsychotic treatment |
| THYM | cis | rs1577917 | 1 | rs12190604 | chr6:86716215 | SNHG5 | chr6:86386726-86388451:- | -0.58 | -6.9 | 5.71E-10 | Response to antipsychotic treatment |
| THYM | cis | rs1577917 | 1 | rs12192992 | chr6:86609915 | SNHG5 | chr6:86386726-86388451:- | -0.57 | -6.96 | 4.28E-10 | Response to antipsychotic treatment |
| THYM | cis | rs1577917 | 1 | rs12196037 | chr6:86694631 | SNHG5 | chr6:86386726-86388451:- | -0.61 | -7.35 | 6.78E-11 | Response to antipsychotic treatment |
| THYM | cis | rs1577917 | 1 | rs12196411 | chr6:86779762 | SNHG5 | chr6:86386726-86388451:- | -0.63 | -7.57 | 2.43E-11 | Response to antipsychotic treatment |
| THYM | cis | rs9473555 | 1 | rs12196937 | chr6:49382808 | CENPQ | chr6:49431096-49460820:+ | -0.24 | -4.37 | 3.16E-5 | Folate pathway vitamin levels |
| THYM | cis | rs9473555 | 1 | rs12196937 | chr6:49382808 | MUT | chr6:49398994-49431031:- | 0.27 | 4.32 | 3.89E-5 | Folate pathway vitamin levels |
| THYM | cis | rs9487094 | 1 | rs12197114 | chr6:109735498 | MICAL1 | chr6:109765268-109787171:- | -0.17 | -4.41 | 2.69E-5 | Height |
| THYM | cis | rs1577917 | 1 | rs12199516 | chr6:86726221 | SNHG5 | chr6:86386726-86388451:- | -0.57 | -6.89 | 5.95E-10 | Response to antipsychotic treatment |
| THYM | cis | rs1577917 | 1 | rs12199784 | chr6:86726808 | SNHG5 | chr6:86386726-86388451:- | -0.57 | -6.89 | 5.95E-10 | Response to antipsychotic treatment |
| THYM | cis | rs1577917 | 1 | rs12200330 | chr6:86656653 | SNHG5 | chr6:86386726-86388451:- | -0.57 | -6.96 | 4.28E-10 | Response to antipsychotic treatment |
| THYM | cis | rs1577917 | 1 | rs12201571 | chr6:86609750 | SNHG5 | chr6:86386726-86388451:- | -0.57 | -6.89 | 5.95E-10 | Response to antipsychotic treatment |
| THYM | cis | rs1577917 | 1 | rs12201735 | chr6:86656939 | SNHG5 | chr6:86386726-86388451:- | -0.57 | -6.89 | 5.95E-10 | Response to antipsychotic treatment |
| THYM | cis | rs1577917 | 1 | rs12201741 | chr6:86602619 | SNHG5 | chr6:86386726-86388451:- | -0.57 | -6.89 | 5.95E-10 | Response to antipsychotic treatment |
| THYM | cis | rs1577917 | 1 | rs12201880 | chr6:86627007 | SNHG5 | chr6:86386726-86388451:- | -0.57 | -6.89 | 5.95E-10 | Response to antipsychotic treatment |